Low tidal volume ventilation (LTVV) is referred to as lung protective ventilation that aims to avoid alveolar over-distension, which is one of the principal mechanisms of ventilator-induced lung injury (VILI). The incidence of barotrauma during mechanical ventilation varies with the underlying indication for mechanical ventilation but ranges from 0%-50%. It may lead to alveolar rupture resulting in the release of air into extra-alveolar spaces. Positive pressure ventilation is non physiologic and may cause adverse effects including pulmonary barotrauma and its associated negative consequences on the lung. The overall frequency of respiratory failure is not well known, for which patients require mechanical ventilation. Respiratory failure is a syndrome rather than a single disease process. Age, gender, BMI, and PCO2 have significant correlation with adherence to LTVV practice. Practice adherence is not different over weekend or night shifts. There was no significant difference between day and night shifts or weekday and weekend shifts. Stepwise multiple regression analysis shows that age, gender, body mass index (BMI), and partial pressure of carbon dioxide (PCO2) have significant correlation with adherence to LTVV practice.Ĭonclusion: The study found that adherence to lung protective low tidal volume mechanical ventilation practice is low. Results: The sample size was 101 patients with 870 patient-ventilator days with 1734 patient ventilator shifts. Clinical variables were recorded to analyze predictors of adherence pattern. Adherence rates for weekday shifts were compared with those of weekend shifts. Adherence rates were calculated and adherence rates of daytime shifts were compared to those of night time shifts. Adherence was determined by comparing these tidal volumes to standard low tidal volumes of 6 ml/kg of ideal body weight. Methods: Tidal volume for mechanically ventilated patients were recorded for each 12-hour shift, day and night shifts for consecutive 101 patients. Background: Low tidal volume ventilation (LTVV) strategy improves outcomes however, despite recommended by guidelines, adherence to this practice is not high.
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